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Microarray Bioinformatics
Cambridge University Press - (ISBN-13: 9780521525879)
Published November 2003
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Price:
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£ 32.00
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Author(s):
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Dov Stekel
University of Birmingham
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Description:
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This book is a comprehensive guide to all of the mathematics, statistics
and computing you will need to successfully operate DNA microarray
experiments. It is written for researchers, clinicians, laboratory heads
and managers, from both biology and bioinformatics backgrounds, who work
with, or who intend to work with microarrays. The book covers all
aspects of microarray bioinformatics, giving you the tools to design
arrays and experiments, to analyze your data, and to share your results
with your organization or with the international community. There are
chapters covering sequence databases, oligonucleotide design,
experimental design, image processing, normalization, identifying
differentially expressed genes, clustering, classification and data
standards. The book is based on the highly successful Microarray
Bioinformatics course at Oxford University, and therefore is ideally
suited for teaching the subject at postgraduate or professional level.
• A balanced and comprehensive guide to all microarray bioinformatics,
accessible to students from both biology and bioinformatics backgrounds
• Based on the highly successful microarray bioinformatics course at
Oxford University and written by the course's director, an experienced
instructor • Detailed glossary of terms provided by the Microarray Gene
Expression Data Society, who defines the standard terms used in the
field internationally.
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Contents List:
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1. Microarrays: making them and using them; 3. Sequence databases
for microarray 4. Computer design of oligonucleotide probes,
5. Image Processing, 6. Normalization 7. Measuring and quantifying
microarray variability, 8. Analysis of differentially expressed genes,
9. Analysis of relationships between genes, tissues or treatments; 10.
Classification of tissues and samples, 11. Experimental Design; 11. Data
storage, standards and sharing; Appendix A. Glossary.
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Reviews:
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'The author does an excellent job of covering high-level
analysis of microarray data… [the book] provides the
statistically naive biologist with a gentle introduction to
the data transformations and manipulations needed to deal
with microarrays, and the examples worked with publicly
available data are well described… excellent value for any
budding array… '. Nature Genetics.
'… Excellent and clearly written… a pleasure to read. "ASM News.
'The book would be ideal for biologists
who wish to gain a grasp of the different analysis
techniques available to the microarray user. " Microbiology Today.
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Publisher:
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Cambridge University Press.
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