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Viruses and Apoptosis v. 36 (Progress in Molecular & Subcellular Biology S.) 356 pages - hardback Springer-Verlag Berlin and Heidelberg GmbH & Co. K - (isbn 3-540-20228-5) Mar. 2004 |
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| Price: |
197,51 EUR
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| Editor: |
Alonso, Covadonga
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| Description: |
The
interactions between viruses and the cells they infect include the
virus control of cellular functions to their advantage. The cell
counteracts with a defensive immune system and stress responses. Both
sides of this struggle include modifications in the cell death program
that will be crucial for the infection outcome. In this book, molecular
pathways regulated by viral genes and their role in the pathogenesis of
infection are analysed in different viral models. It also includes a
didactic update of known signaling pathways in apoptosis and their role
in normal and infected cells. Special emphasis was given to molecular
pathways underlying viral transformation and oncogenesis and to the
perspectives in cancer gene therapy. Particular cell types in apoptosis
such as neuronal cells and lymphoid cell death are also emphasized.
This book is designed to give an in-depth update of viral gene
interaction with regulation pathways in apoptosis for scientists and
researchers in the fields of molecular biology, virology, cell biology,
oncology, and neurobiology.
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| Contents List: |
Cell
Death Suppressors Encoded by Cytomegalovirus * Apoptosis Regulator
Genes Encoded by Poxvirus * T Cell Mediated Control of Poxvirus
Infection in Mice * Switching on and off the Cell Death Cascade:
African Swine Fever Virus Apoptosis Regulation * Sindbis Virus Induces
Neuronal Cell Death and Lethal Encephalitis * Apoptosis Pathways
Triggered by HIV and Consequences on T Cell Homeostasis and
HIV-Specific Immunity * HIV and Apoptosis: A Complex Interaction
Between Cell Death and Virus Survival * Poliovirus and Apoptosis *
Flaviviruses and Apoptosis Regulation * Manipulatin of Apoptosis by
Herpes Viruses (Kaposi's Sarcoma Pathogenesis) * Exploitation of Cell
Cycle and Cell Death Controls by Adenoviruses: The Road to a Productive
Infection * Induction of Transformed Cell-Specific Apoptosis by the
Adenvirus E4ORF4 Protein * Epstein-Barr Virus Signal Transduction and
B-Lymphocyte Growth Transformation * SV40 and NOTCH-I:
Multifunctionality Meets Pleiotropy * Signal Transduction and Apoptosis
Pathways as Therapeutic Agents *
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| Illustrations etc.: | 26 illustrations, 5 tables | |||||||
| Weight: | 794 g | |||||||
| Dimensions: | 248 x 165 | |||||||
| Publisher: | Springer-Verlag Berlin and Heidelberg GmbH & Co. KG | |||||||
| Springer-Verlag | ||||||||